Catalog Number - 68040-P21-PG1-3

Cogent NP Amino Wide Pore Prep Guard Column Cartridges are packed with the same propyl amino bonded stationary phase used in Cogent NP Amino Wide Pore preparative columns. Manufactured on high-purity 300 Å wide pore silica, these guard cartridges protect the preparative column from particulates, strongly retained contaminants, and sample matrix components that can reduce chromatographic performance and shorten column life. The amino functionality provides excellent retention of polar compounds in both Normal Phase and HILIC applications while maintaining USP L8 selectivity.

68040-P21-PG1-3 is a preparative guard column cartridge packed with 10 µm NP Amino Wide Pore particles featuring a 300 Å pore size in a 21.2 mm ID x 10 mm format. Installed ahead of the preparative column, it captures contaminants before they reach the analytical bed, helping maintain chromatographic efficiency, improve reproducibility, and extend column lifetime in demanding purification applications.

This guard cartridge is designed specifically for use with 21.2 mm ID Cogent NP Amino Wide Pore preparative columns and is housed in durable stainless-steel hardware with stainless-steel frits for reliable operation under preparative flow conditions. The wide pore structure improves accessibility for larger molecules including complex carbohydrates and other high molecular weight polar compounds.

Key Benefits

• NP Amino Wide Pore stationary phase

• USP L8 equivalent chemistry

• Propyl amino bonded phase

• 300 Å wide pore silica

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Protects preparative columns from particulates and contaminants

• Helps maintain column efficiency and reproducibility

• Extends preparative column lifetime

• Stainless steel cartridge construction

Typical Applications

• Preparative chromatography

• USP L8 methods

• HILIC separations

• Normal Phase chromatography

• Complex sugar purification

• Carbohydrate purification

• Organic acid purification

• Pharmaceutical purification

• Sample cleanup prior to preparative separation

• Preparative column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: NP Amino Wide Pore

• USP Classification: L8

• Chromatography Mode: Normal Phase / HILIC

• Bonded Phase: Propyl Amino

• Endcapping: Not Endcapped

• Particle Size: 10 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 1 EA

• Brand: Cogent

Guard Column Holder Requirement

• A 21.2 mm ID Prep Guard Column Holder is required for use with this guard cartridge.

• View the Cogent 21.2 mm ID Prep Guard Column Holder (83000-P21-GH)

Special Order Item Information

• Contact Customer Service for quotation, lead time, and ordering assistance.

• Learn more about Special Order Items and ordering policies.

Important Notes

• Packed and shipped in Normal Phase solvents

• Suitable for both Normal Phase and HILIC chromatographic modes

• Wide pore design improves access for larger molecules and complex carbohydrates

• Designed for use with 21.2 mm ID NP Amino Wide Pore preparative columns

• Helps protect preparative columns from contamination and premature fouling

• Requires a specialized preparative HPLC system compatible with 21.2 mm ID columns

• This is a Special Order Item